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    Posts tagged "mutation"

    Tuesday, Sep 1st, 2009 ↓

    Breast Cancer: Risk Increases For Smokers And Overweight Women →

    Sept 1, 2009 (Sciencedaily.com)—A recent study published in the Journal of Cancer Epidemiology has reinforced the correlation between being overweight, smoking and breast cancer. What makes this study unique is how test subjects were not diagnosed for BRCA1 and BRCA2 gene mutations, which predispose women to breast cancer.

    Instead, women with such gene mutations were excluded to allow researchers to concentrate on lifestyle factors such as smoking, exercise, nutrition and weight. All women analyzed in the study were direct ancestors of the first French colonists.

    “To our knowledge, this is the first study conducted on a sample of women without BRCA1 and BRCA2 gene mutations, which are often found in French-Canadian women,” says lead researcher Vishnee Bissonauth, a graduate of the Université de Montréal’s Department of Nutrition and a researcher at the Sainte-Justine University Hospital Research Center.

    For full article, see link above.

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    Tags: smoking breast cancer risk overweight obesity cigarette smoker gene mutation correlation
    Friday, Jul 10th, 2009 ↓

    Enzyme Fights Mutated Protein In Inherited Parkinson's Disease →

    July 10, 2009 (Sciencedaily.com)—An enzyme that naturally occurs in the brain helps destroy the mutated protein that is the most common cause of inherited Parkinson’s disease, researchers at UT Southwestern Medical Center have found.

    Their study, using human cells, provides a focus for further research into halting the action of the mutated protein. One of the most famous carriers of the mutation is Google co-founder Sergey Brin, who wrote about it on his blog in 2008.

    “There are currently enormous efforts to identify potential therapies based on inhibiting this mutated protein,” said Dr. Matthew Goldberg, assistant professor of neurology and psychiatry and senior author of the paper, which appears online in the journal Public Library of Science.

    For full article see link above.

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    Tags: parkinson's. enzyme inherited disease mutation brain neurology
    Tuesday, May 12th, 2009 ↓

    Pollution Causes Genetic Changes that Lead to Asthma →

    May 10 09 (NaturalNews) Prenatal exposure to air pollution appears to cause genetic changes that predispose unborn infants to asthma later in life, according to a new study conducted by researchers from the Center for Environmental Genetics a the University of Cincinnati and published in the journal PLoS ONE.

    “Our data support the concept that environmental exposures can interact with genes during key developmental periods to trigger disease onset later in life, and that tissues are being reprogrammed to become abnormal later,” lead researcher Shuk-mei Ho said.

    Researchers had pregnant women wear backpack air monitors that analyzed the women’s exposure to polycyclic aromatic hydrocarbons (PAHs), a type of pollution produced by combustion that is characteristic of the air in high-traffic areas. The researchers also examined the expression of the ACSL3 gene in their unborn children.

    For full article, see link above.

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    Tags: pollution genetic mutation infant asthma breathing