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    Posts tagged "multivitamin"

    Tuesday, Sep 1st, 2009 ↓

    Antioxidants Not Associated With Increased Melanoma Risk →

    Sept 1. 2009 (Sciencedaily.com)—Antioxidant supplements do not appear to be associated with an increased risk of melanoma, according to a new report.

    A recent randomized trial of antioxidants for cancer prevention found that daily supplementation with nutritionally appropriate doses of vitamins C and E, beta carotene, selenium and zinc appeared to increase the risk of melanoma in women four-fold, according to background information in the article. Because an estimated 48 percent to 55 percent of U.S. adults use vitamin or mineral supplements regularly, the potential harmful effects of these nutrients is alarming, the authors note.

    Maryam M. Asgari, M.D., M.P.H., of Kaiser Permanente Northern California, Oakland, and colleagues examined the association between antioxidants and melanoma among 69,671 women and men who were participating in the Vitamins and Lifestyle (VITAL) study, designed to examine supplement use and cancer risk. At the beginning of the study, between 2000 and 2002, participants completed a 24-page questionnaire about lifestyle factors, health history, diet, supplement use and other cancer risk factors.

    Intake of multivitamins and supplements during the previous 10 years, including selenium and beta carotene, was not associated with melanoma risk in either women or men. The researchers also examined the risk of melanoma associated with long-term use of supplemental beta carotene and selenium at doses comparable to the previous study and found no association.

    “Consistent with the present results, case-control studies examining serologic [blood] levels of beta carotene, vitamin E and selenium did not find any association with subsequent risk of melanoma,” the authors write. “Moreover, the Nurses’ Health Study reported no association between intake of vitamins A, C and E and melanoma risk in 162,000 women during more than 1.6 million person-years of follow-up.”

    For full article, see link above.

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    Tags: antioxidant supplement vitamin mineral C e beta carotene selenium zinc cancer risk nutrient melanoma lifestyle multivitamin
    Monday, Jul 20th, 2009 ↓

    Multivitamins may lower heart disease death risk →

    July 20, 2009 (nutraingredients.com)—Long-term regular consumption of a multivitamin may reduce the risk of dying from heart disease by 16 per cent, according to a new study from the US.

    Intakes of vitamin E over 215 milligrams per day over the course of ten years were also associated with a 28 per cent reduction in the risk of death from cardiovascular disease, according to findings published in the American Journal of Epidemiology.

    The news supports the use of multivitamins and particularly vitamin E, much-maligned and linked to increased risk of ‘all-cause mortality’ in a controversial meta-analysis in the Annals of Internal Medicine in 2004.

    The new study, led by Gaia Pocobelli from Fred Hutchinson Cancer Research Center at the University of Washington, also contradicts conclusions from a controversial meta-analysis published originally in the Journal of the American Medical Association (2007, Vol. 297, pp. 842-857). The meta-analysis reported that supplements of vitamins A and E, and beta-carotene may increase mortality risk by up to 16 per cent. On the other hand, vitamin C did not have an effect on mortality.

    In terms of other causes of death, Pocobelli report that multivitamins did not decrease the risk of either total mortality, or cancer mortality. On the other hand, vitamins C and E were associated with small decreases in risk of total mortality.

    For full article see link above.

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    Tags: multivitamin heart disease risk death vitamin e cardiovascular c