Dr. John's Health Matters
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The articles posted here are from various sources who are duly acknowledged. I would appreciate being immediately notified, if any copywritten material needs to be removed. This blog is not intended to replace the qualified advice of a licensed health practitioner. Readers should exercise their own judgment. Enjoy, subscribe, participate and tell others :)
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Posts tagged "heart"
Tuesday, Sep 1st, 2009 ↓Caution on mix of cholesterol-lowering meds →
Sept 1, 2009 (Cbc.ca)—Combining a prescription cholesterol-lowering medication with omega-3 supplements may not be the best approach, a new review suggests.
Statins are medications that prevent the liver from producing cholesterol, which can help reduce the risk of heart attacks. Every year, Canadian doctors write more than 12 million prescriptions for statins, making them the most-prescribed drugs in the country. Omega-3’s are heart-healthy oils that some evidence suggests help reduce the risk of coronary disease.
In the Nov. 3 issue of the Annals of Internal Medicine, Dr. Mukul Sharma, medical director of the Regional Stroke Centre at the Ottawa Hospital, and his team reviewed five different cholesterol-lowering medications that can be combined as well as omega-3 supplements sold over the counter. They concluded there is little evidence to support mixing them.
Bad cholesterol increase
In one case, the researchers found taking prescription medication with omega-3 had the opposite effect.
“Your bad cholesterol, the LDL, actually goes up,” Sharma said. “There isn’t a benefit in terms of heart disease, stroke or mortality.”
Most cholesterol patients may be better off taking higher doses of one drug instead of multiple medications, since there may be less chance of side-effects and long-term problems developing, he said. People are also less likely to take their medications the more that are prescribed.
For full article, see link above.
Tags: cholesterol increase risk danger LDL prescription cardiovascular blood heart statin medication liver heart attack prevention coronary disease
Heart Suffers From Just a Few Whiffs of Smoke →
Sept 1, 2009 (Therapytimes.com)—Just a few whiffs of tobacco smoke or dirty air can have a profound negative impact on your heart’s health.
Study results released today by the American Heart Association suggest that exposure to even a small amount of smoke — whether it’s from your own cigarette or someone else’s — greatly increases your risk of dying from cardiovascular disease. The same goes for breathing in air polluted with carbon monoxide emissions.
“It doesn’t require extreme exposure to have significant cardiovascular effects. Even passive exposures to ambient air pollution and secondhand smoke contribute to significant increases in cardiovascular mortality,” study author C. Arden Pope III, PhD, says in a statement.
For full article, see link above.
Tags: heart cardiovascular risk disease smoke tobacco risk danger exposure cigarette breathing air pollution
How Much Omega-3 Fatty Acid Do We Need To Prevent Cardiovascular Disease? →
Sept 1, 2009 (Sciencedaily.com)—A team of French scientists have found the dose of DHA (docosahexaenoic acid) that is “just right” for preventing cardiovascular disease in healthy men. In a research report appearing in the September 2009 print issue of The FASEB Journal, the scientists show that a 200 mg dose of DHA per day is enough to affect biochemical markers that reliably predict cardiovascular problems, such as those related to aging, atherosclerosis, and diabetes. This study is the first to identify how much DHA is necessary to promote optimal heart health.
“This study shows that regularly consuming small amounts of DHA is likely to improve the health status of people, especially in regards to cardiovascular function,” said Michel Lagarde, co-author of the study.
To determine the optimal dose of DHA, Lagarde and colleagues examined the effects of increasing doses of DHA on 12 healthy male volunteers between ages of 53 and 65. These men consumed doses of DHA at 200, 400, 800, and 1600 mg per day for two weeks for each dose amount, with DHA being the only omega-3 fatty acid in their diet. Blood and urine samples were collected before and after each dose and at eight weeks after DHA supplementation stopped. The researchers then examined these samples for biochemical markers indicating the effects of each dose on the volunteers.
“Now that we have a very good idea about how much DHA is just right, the next step is to try it out in an expanded clinical trial that involves many more people,” said Gerald Weissmann, M.D., Editor-in-Chief of The FASEB Journal. “Until then, I’ll stick with tasty foods that contain DHA, like fish, rather than getting a quick fatty-acid fix at the local vitamin store.”
Journal reference:
- Nicolas Guillot, Emilie Caillet, Martine Laville, Catherine Calzada, Michel Lagarde, and Evelyne Véricel. Increasing intakes of the long-chain -3 docosahexaenoic acid: effects on platelet functions and redox status in healthy men. The FASEB Journal, 2009; 23 (9): 2909 DOI: 10.1096/fj.09-133421
Tags: omega fatty acid DHA heart cardiovascular supplement disease prevention atherosclerosis diabetes
Surprising Rate Of Recurring Heart Attacks, Strokes Globally →
Aug 31, 2009 (Sciencedaily.com)—Despite many medicines and other treatments for patients with vascular disease, a large international study shows these patients have a surprisingly high rate of recurring events such as strokes, heart attacks and hospitalizations as well as mortality.
Also unexpected: patients in North America (including the U.S.) experienced an above-average rate of these events. Patients in Eastern Europe had the highest rate, and those in Australia and Japan had the lowest.
The results from the international REACH (Reduction of Atherothrombosis for Continued Health) Registry, presented by a researcher from Northwestern University Feinberg School of Medicine, examined data for 32,247 patients one and three years after they enrolled in the registry. Patients who had symptomatic vascular disease had a 14.4 percent rate at one year and 28.4 percent rate at three years of having a heart attack, stroke, rehospitalization for another type of vascular event or vascular death. Patients with vascular disease in more than one location of the body had the highest event rate at 40.5 percent at three years.
When projected over the global population who would mirror the patients in REACH, this represents millions of serious vascular events occurring every few years, many of which could be prevented.
“We were surprised by the high rate of these recurring vascular events,” said lead author Mark J. Alberts, M.D., professor of neurology at the Feinberg School and director of the stroke program at Northwestern Memorial Hospital. “We know how to prevent vascular disease and the events that it produces. This points to the need for better prevention, better use of medications and a need to develop more potent medications. These are the number one and two causes of death throughout the world.”
For full article, see link above.
Tags: heart attack cardiovascular blood vessel stroke reoccurance rehospitalization disease prevention risk
Exercise beats angioplasty: heart experts →
Aug 31, 2009 (Cbc.ca)—Working up a sweat may be even better than angioplasty for some heart patients, experts say.
Studies have shown heart patients benefit from exercise, and some have shown it works better than surgical procedures. At a meeting of the European Society of Cardiology in Barcelona on Sunday, several experts said doctors should focus more on persuading their patients to exercise rather than simply doing angioplasties.
Angioplasty is the top treatment for people having a heart attack or hospitalized with worsening symptoms. It involves using a tiny balloon to flatten a blockage and propping the heart artery open with a mesh tube called a stent. Most angioplasties are done on a non-emergency basis, to relieve chest pain caused by clogged arteries cutting off the heart’s blood supply.
“It’s difficult to convince people to exercise instead of having an angioplasty, but it works,” said Rainer Hambrecht of Klinikum Links der Weser in Bremen, Germany.
Hambrecht published a study in 2004 that found that nearly 90 per cent of heart patients who rode bikes regularly were free of heart problems one year after they started their exercise regimen. Among patients who had an angioplasty instead, only 70 per cent were problem-free after a year.
For full article, see link above.
Tags: exercise heart attack angioplasty cardiovascular physical activity surgery artery chest pain clogged blood flow prevention
Whey Protein Improves Heart Health →
Aug 31, 2009 (Mercola.com)—A whey-protein-rich ingredient may improve blood vessel function in healthy individuals, reports a new randomized, double-blind study.
Two weeks of supplementation resulted in a 1.5 percent improvement in blood flow. According to the researchers, the whey protein-derived ingredient may work via an angiotensin converting enzyme (ACE)-inhibitory activity.
ACE inhibitors work by inhibiting the conversion of angiotensin I to the potent vasoconstrictor, angiotensin II, thereby improving blood flow and blood pressure.
Sources:
NutraIngredients August 5, 2009Nutrition Journal July 22, 2009; 8:34 [Free Full-Text Article]
Tags: whey protein heart cardiovascular blood vessel supplement angiotensin vascoconstrictor flow
Obesity Is A Poor Gauge For Detecting High Cholesterol Levels In Children →
Aug 29, 2009 (Sciencedaily.com)—With the epidemic of childhood obesity in the United States, there is concern that overweight and obese children need to be screened for chronic medical conditions, including high cholesterol levels.
However, body fat is not an effective indicator of high cholesterol in children, according to new University of Michigan research.
Those are the findings of a U-M study led by U-M pediatricians Joyce Lee, M.D., MPH, and Matthew Davis, M.D., MAPP, which will appear in the August 3 edition of the Archives of Pediatric and Adolescent Medicine.
“We found, actually, that using body mass index to find kids with high cholesterol does not work well. There were many overweight and obese kids who had normal cholesterol, and there were a fair number of healthy-weight kids who had high cholesterol,” says Lee, a member of the Child Health Evaluation and Research (CHEAR) Unit in the U-M Division of General Pediatrics, and assistant professor in the Department of Pediatrics and Communicable Diseases at the U-M Medical School.
For full article see link above.
Tags: obesity weight cholesterol heart cardiovascular disease body fat BMI children child overweight prevention screening risk
Consumers Duped by Trans Fat Labeling →
Aug 28, 2009 (NaturalNews.com)— FDA food labeling rules make it possible for consumers to exceed their maximum recommended daily intake of trans fats even if they eat only foods labeled “zero trans fats” per serving.
Trans fats, also known as hydrogenated oils, are synthetically produced by adding hydrogen atoms to unsaturated vegetable oils. Unlike natural unsaturated or saturated fats, trans fats have no nutritional value. They have been overwhelmingly shown to increase the risk of death from cardiovascular disease, such that several large cities and the state of California have banned their use in restaurants.
The fats are favored by food producers because they have a longer shelf life than natural fats. But growing consumer awareness over the dangers of trans fats has led more and more people to avoid them. According to a recent survey by Greenfield Online, 72 percent of U.S. residents read nutritional labels to make food purchasing decisions, and 61 percent believe that “zero trans fats” is the most important claim for a heart-healthy food.
Yet because the FDA allows nutrient content to be rounded to the nearest half gram, all food producers need to do to make a “zero trans fats” claim is set the serving size low enough that it contains no more than 0.49 grams of trans fats.
For full article, see link above.
Tags: labeling rule FDA transfat fat nutrition diet prevention obesity cardiovascular heart disease food vegetable oil daily intake
AHA limits sugar intake to protect heart →
Aug 27, 2009 (Presstv.com)—While Americans eat more than 22 teaspoons of sugar per day, the American Heart Association urges individuals to limit their sugar intake in order to remain healthy.
“For the first time we’ve created specific recommendations about the amount of sugars that can be consumed in a heart-healthy diet,” said Rachel Johnson lead author of a report published in Circulation.
According to the report, too much sugar not only leads to obesity but also places the individual at a greater risk of developing diabetes, high blood pressure, heart disease and stroke.
The new guidelines revealed that women should eat less than 100 calories (equal to six teaspoons or 25 grams) of added processed sugar per day.
The limit for moderately active women aged 51-55 is as low as 5 teaspoons (80 calories) and for sedentary women aged 71-75 is as low as 3 teaspoons (48 calories).
As for men, the permitted sugar amount is reported to be less than 150 calories, equal to nine teaspoons or 37.5 grams.
The new guidelines recommend active men aged 21-25 to eat less than 18 teaspoons (288 calories) and sedentary men aged 46-50 to eat less than 9 teaspoons (144 calories).
AHA officials say that the guidelines are only for “added sugars” used to make foods and drinks rather than the natural sugar found in fruits, vegetables, whole grains, or milk.
They therefore urged food and beverage companies to limit the sugar content of their products.
PKH/HGH
Tags: heart disease cardiovascular disease diabetes high blood pressure hypertension stroke diet nutrition teaspoon calorie processed sugar content limit risk
Hormone therapy fatal in prostate cancer sufferers →
Aug 27, 2009 (Presstv.com)—Hormone-based medications commonly used to treat aggressive prostate cancer may be hazardous for certain men suffering from heart problems.
Previous studies had reported that drugs which block tumor-fueling surges of testosterone can effectively treat aggressive forms of prostate cancer.
A new study, however, finds radiation therapy added with these drugs increase the mortality rate in men already suffering from heart disease.
According to the study published in the Journal of the American Medical Association, neoadjuvant hormone therapy doubles the risk of death in prostate cancer sufferers with coronary artery disease-induced congestive heart failure (CHF) and myocardial infarction (MI).
Such a high mortality risk, however, was not reported among those with no comorbidity or just a single coronary disease risk factor undergoing the treatment.
Scientists concluded that physicians should prescribe hormone therapy with care in men with serious heart diseases. Such men account for only five percent of the male population.
PKH/AA
Tags: hormone therapy prostate cancer danger risk heart disease cardiovascularr testosterone death coronary artery congestive heart failure heart attack myocardial infarction treatment
Tags: supplement metabolic syndrome cardiovascular heart blood pressure extract root obesity cholesterol insulin isoflavone kudzu stroke disease
Using Cranberry Juice To Combat Urinary Tract Infections 'Inconclusive' →
Aug 25, 2009 (Sciencedaily.com)—Current clinical evidence for using cranberry juice to combat urinary tract infections is ‘unsatisfactory and inconclusive’, according to Raul Raz.
Not all medical problems require a state-of-the-art solution, and it would be nice to think that products from the corner shop could treat a widespread and uncomfortable ailment. Cranberry juice and related products have been touted as a simple solution for urinary tract infections, but Raul Raz, a member of F1000 Medicine, finds little to support this claim.
Urinary tract infections (UTIs) are a common complaint. Between 10% and 20% of women will suffer a UTI at least once, and a third of these will experience it recurrently. Some recent studies support the use of cranberry as a preventative, but Dr Raz, Director of Infectious Diseases at the Technion School of Medicine in Israel, and his associate Faculty Member, Hana Edelstein, advise the medical community that “cranberry should no longer be considered as an effective [preventative] for recurrent UTIs”.
Cranberry contains hundreds of compounds, and it has been difficult to determine which might be responsible for any therapeutic effect, hindering its adoption. Raz and Edelstein point to differences in clinical trial design and the lack of standardization for doses and formulation. There is a range of potential side-effects including stomach upsets and weight gain. Cranberry can also interact badly with other medicines such as Warfarin, commonly used to treat heart disease.
For full article, see link above.
Tags: cranberry urinary tract infection juice prevention therapeutic stomach upset interaction medication heart disease
Why Low Vitamin D Raises Heart Disease Risks In Diabetics →
Aug 25, 2009 (sciencedaily.com)—Low levels of vitamin D are known to nearly double the risk of cardiovascular disease in patients with diabetes, and researchers at Washington University School of Medicine in St. Louis now think they know why.
They have found that diabetics deficient in vitamin D can’t process cholesterol normally, so it builds up in their blood vessels, increasing the risk of heart attack and stroke. The new research has identified a mechanism linking low vitamin D levels to heart disease risk and may lead to ways to fix the problem, simply by increasing levels of vitamin D.
“Vitamin D inhibits the uptake of cholesterol by cells called macrophages,” says principal investigator Carlos Bernal-Mizrachi, M.D., a Washington University endocrinologist at Barnes-Jewish Hospital. “When people are deficient in vitamin D, the macrophage cells eat more cholesterol, and they can’t get rid of it. The macrophages get clogged with cholesterol and become what scientists call foam cells, which are one of the earliest markers of atherosclerosis.”
Macrophages are dispatched by the immune system in response to inflammation and often are activated by diseases such as diabetes. Bernal-Mizrachi and his colleagues believe that in diabetic patients with inadequate vitamin D, macrophages become loaded with cholesterol and eventually stiffen blood vessels and block blood flow.
For full article, see link above.
Tags: vitamin d diet nutrition diabetes deficient blood vessel heart attack stroke danger rosk cholesterol atherosclerosis immunity disease
Another Danger from High Glycemic Foods: Research Shows They Damage Arteries →
Aug 25, 2009 (NaturalNews.com)— Anyone interested in healthy and nutritious foods has probably heard that whole grains are far better for you than the processed variety like white bread and sugar-laden cereals. There are several reasons for this, including the fact whole foods tend to be richer in fiber and they also have low glycemic indexes. That means they keep blood sugar and insulin levels steady without wide fluctuations. But a new study published in the Journal of the American College of Cardiology concludes there’s another important reason to avoid high glycemic foods like white bread and corn flakes. For the first time, scientists have documented how eating these foods can directly damage artery walls and cause cardiac problems.
“It’s very hard to predict heart disease,” Dr. Michael Shechter of Tel Aviv University’s Sackler School of Medicine and the Heart Institute of Sheba Medical Center, said in a statement to the media. “But doctors know that high glycemic foods rapidly increase blood sugar. Those who binge on these foods have a greater chance of sudden death from heart attack. Our research connects the dots, showing the link between diet and what’s happening in real time in the arteries.”
For full article, see link above.
Tags: damage artery cardiovasculat gylcemic food sugar wall heart blood sugar attack diet
Diabetes Drug Linked To Increased Risk Of Heart Failure →
Aug 24, 2009 (Sciencedaily.com)—Rosiglitazone, a drug used to treat type 2 diabetes, is associated with an increased risk of heart failure and death among older patients compared to a similar drug (pioglitazone), concludes a study published on bmj.com.
As such, the researchers say it is difficult to advocate continued use of rosiglitazone for most patients.
Rosiglitazone and pioglitazone belong to a class of drugs called thiazolidinediones and are widely used for the treatment of type 2 diabetes. They help to control blood sugar levels, but both drugs can also cause side effects including weight gain, fluid retention and heart failure.
It is unclear whether there are clinically important differences in the cardiac safety of these two drugs, so researchers in Canada compared the risk of heart attack, heart failure and death in patients treated with rosiglitazone and pioglitazone.
Using prescription records, they identified nearly 40,000 patients aged 66 years and older who started treatment with either rosiglitazone or pioglitazone between April 2002 and March 2008.
Data on hospital admission for either a heart attack or heart failure during the six-year study period were recorded and deaths were identified from a national database.
Detailed analysis showed that patients treated with pioglitazone had a significantly lower risk of heart failure and death compared to patients treated with rosiglitazone, but there was no significant difference in the risk of heart attack.
The researchers estimate that, for every 93 patients treated with rosiglitazone rather than pioglitazone, one additional cardiovascular event or death would be predicted to occur annually.
“Our findings suggest clinically important differences in the cardiovascular safety profiles of rosiglitazone and pioglitazone in clinical practice,” say the authors. “Given the accumulating evidence of harm with rosiglitazone treatment and the lack of a distinct clinical advantage for the drug over pioglitazone, it is reasonable to question whether ongoing use of rosiglitazone is justified,” they conclude.
For full article see link above.
