Dr. John's Health Matters
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Posts tagged "DHA"
Tuesday, Sep 1st, 2009 ↓How Much Omega-3 Fatty Acid Do We Need To Prevent Cardiovascular Disease? →
Sept 1, 2009 (Sciencedaily.com)—A team of French scientists have found the dose of DHA (docosahexaenoic acid) that is “just right” for preventing cardiovascular disease in healthy men. In a research report appearing in the September 2009 print issue of The FASEB Journal, the scientists show that a 200 mg dose of DHA per day is enough to affect biochemical markers that reliably predict cardiovascular problems, such as those related to aging, atherosclerosis, and diabetes. This study is the first to identify how much DHA is necessary to promote optimal heart health.
“This study shows that regularly consuming small amounts of DHA is likely to improve the health status of people, especially in regards to cardiovascular function,” said Michel Lagarde, co-author of the study.
To determine the optimal dose of DHA, Lagarde and colleagues examined the effects of increasing doses of DHA on 12 healthy male volunteers between ages of 53 and 65. These men consumed doses of DHA at 200, 400, 800, and 1600 mg per day for two weeks for each dose amount, with DHA being the only omega-3 fatty acid in their diet. Blood and urine samples were collected before and after each dose and at eight weeks after DHA supplementation stopped. The researchers then examined these samples for biochemical markers indicating the effects of each dose on the volunteers.
“Now that we have a very good idea about how much DHA is just right, the next step is to try it out in an expanded clinical trial that involves many more people,” said Gerald Weissmann, M.D., Editor-in-Chief of The FASEB Journal. “Until then, I’ll stick with tasty foods that contain DHA, like fish, rather than getting a quick fatty-acid fix at the local vitamin store.”
Journal reference:
- Nicolas Guillot, Emilie Caillet, Martine Laville, Catherine Calzada, Michel Lagarde, and Evelyne Véricel. Increasing intakes of the long-chain -3 docosahexaenoic acid: effects on platelet functions and redox status in healthy men. The FASEB Journal, 2009; 23 (9): 2909 DOI: 10.1096/fj.09-133421
Tags: omega fatty acid DHA heart cardiovascular supplement disease prevention atherosclerosis diabetes
Mounting Evidence Of Fish Oil's Heart Health Benefits →
Aug 5, 2009 (Sciencedaily.com)—There is mounting evidence that omega-3 fatty acids from fish or fish oil supplements not only help prevent cardiovascular diseases in healthy individuals, but also reduce the incidence of cardiac events and mortality in patients with existing heart disease. A new study, published in the August 11, 2009, issue of the Journal of the American College of Cardiology, extensively reviews data from a broad range of studies in tens of thousands of patients and sets forth suggested daily targets for omega-3 consumption.
“This isn’t just hype; we now have tremendous and compelling evidence from very large studies, some dating back 20 and 30 years, that demonstrate the protective benefits of omega-3 fish oil in multiple aspects of preventive cardiology,” said Carl Lavie, M.D., F.A.C.C., medical director of Cardiac Rehabilitation and Prevention, Ochsner Medical Center, New Orleans, LA, and lead author of the article. “The strongest evidence of a cardioprotective effect of omega-3s appears in patients with established cardiovascular disease and following a heart attack with up to a 30 percent reduction in CV-related death.”
Dietary intake of fish oil can also decrease the risk of atherosclerosis, arrhythmias, heart attack, sudden cardiac death and even health failure. Dr. Lavie adds that although there is a smaller benefit in reducing heart failure death—9 percent mortality benefit in a major recent randomized controlled trial—this is still very impressive given patients’ grave prognosis.
For full article see link above.
Tags: fish oil supplement omega fatty acid 3 cardiovascular diet atherosclerosis arrhythmia heart attack failure dha epa prevention
Can Your Diet Prevent Depression? →
July 3, 2009 (Mercola.com)—Depression is an established risk factor for the development of coronary heart disease (CHD). Dietary factors resulting in lower levels of omega-3 fats not only increase CHD risk, but may also cause depression.
Investigators measured red blood cell levels of two omega-3 fats, docosahexaenoic acid (DHA) and eicosapentaenoic acid (EPA), and assessed depressive symptoms in a cross-sectional study of nearly 1,000 adults with CHD.
As EPA and DHA levels rose, depressive symptoms dropped. The prevalence of depression ranged from 23 percent in participants with the lowest blood levels of omega-3 fats to 13 percent in participants with the highest omega-3 blood levels.
Sources:
Tags: depression diet nutrition heart circulatory blood omega 3 RBC DHA CHD EPA prevention
Can Omega-3 Fats Prevent Depression? →
June 16, 2009 (Mercola.com) —Depression is an established risk factor for the development of coronary heart disease (CHD). Dietary factors resulting in lower levels of omega–3 fats not only increase CHD risk, but may also cause depression.
Investigators measured red blood cell levels of two omega–3 fats, docosahexaenoic acid (DHA) and eicosapentaenoic acid (EPA), and assessed depressive symptoms in a cross-sectional study of nearly 1,000 adults with CHD.
As EPA and DHA levels rose, depressive symptoms dropped. The prevalence of depression ranged from 23 percent in participants with the lowest blood levels of omega-3 fats to 13 percent in participants with the highest omega-3 blood levels.
Sources: 
Science Daily June 12, 2009
